Web of knowledge for

IMA - HEALTH

Contract number 481 PED /2020

National Authority: UEFISCDI

UNIVERSITATEA BABES BOLYAI

FACULTATEA DE CHIMIE SI INGINERIE CHIMICA

 

Innovative materials as dietary supplements for healthcare, IMA-HEALTH
Materiale inovative ca suplimente alimentare pentru ingrijirea sanatatii,
IMA-HEALTH

 

 

 

 

 

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OBJECTIVES

EXPECTED RESULTS

OBTAINED RESULTS

DISSEMINATION

 

 

 

 

 

 

·   Phase 1-2 Dissemination:

Research original articles (ISI/BDI)

1. A. Mocanu, O. Cadar, P.T. Frangopol, I. Petean, Gh.Tomoaia, G.A. Paltinean, Cs. P. Racz, O. Horovitz and M. Tomoaia-Cotisel, "Ions release from hydroxyapatite and substituted hydroxyapatites in different immersion liquids. In vitro experiments and theoretical modelling study", R.Soc.OpenSci., 8(1), 1-25, (2021), https://doi.org/10.1098/rsos.201785 (13 January 2021).

2. A. Becze, V.L. Babalau Fuss, D.A. Scurtu , M. Tomoaia-Cotisel, A. Mocanu, O. Cadar, "Simultaneous determination of vitamins D3 (calcitriol, cholecalciferol) and K2 (menaquinone -4 and menaquinone -7) in dietary supplements by UHPLC", Molecules, 26, 1-12, (2021), https://doi.org/10.3390/molecules26226982, (19 November 2021).

3. D. Oltean-Dan, P.T. Frangopol, R. Balint, Gh. Tomoaia, A. Mocanu, M. Tomoaia-Cotisel, "Biocompatibility of titanium implants coated with biocomposite in a rat model of femoral fracture", Studia UBB Chemia, 66(3) 73-87, (2021).

4. R. Balint, I. Petean, P.T. Frangopol, A. Mocanu, G. Arghir, S. Riga, Gh. Tomoaia, O. Horovitz, M. Tomoaia-Cotisel, "Biomimetic nanocomposite structures designed for coating of orthopedic implants: AFM investigation", Studia UBB Chemia, 66(3), 141-160, (2021).

5. A. Mocanu, P.T. Frangopol, R. Balint, O. Cadar, I.M. Vancea, R. Mantiu, O. Horovitz, M. Tomoaia-Cotisel, "Higuchi model applied to ions release from hydroxyapatites", Studia UBB Chemia, 66(3), 195-207, (2021).

6. D. Oltean-Dan, G.-B. Dogaru, E.-M. Jianu, S. Riga, M. Tomoaia-Cotisel, A. Mocanu, L. Barbu-Tudoran, Gh. Tomoaia, "Osseointegration of biomimetic composite coating on titanium implants: in vivo study", Micromachines, 12(11), 1-24, (2021), https://doi.org/10.3390/mi12111352, (31 October 2021).

7. R. Balint, G.A. Paltinean, Gh. Tomoaia, D. Oltean-Dan, A. Mocanu, M. Tomoaia–Cotisel, "Biomaterials with enhanced biological functions for medical applications", Academy of Romanian Scientists Annals Series on Biological Sciences, 10(1), 90-145 (2021).


Communications at conferences

1. A. Becze, V. Babalau-Fuss, E.A. Levei, O. Cadar, "A novel high pressure liquid chromatographic method for the determination of vitamin D3 in simulated human gastrointestinal tract", XXI EuroFoodChem, 22-24 November 2021 - poster (online).

2. O. Cadar, Talented organisations in NMP from Romania, INCDO INOE Research Institute for Analytical Instrumentation, Cluj-Napoca, "Driving talented organisations to successful Horizon Europe projects", event organized by FIT-4-NMP H2020 project at the 44th International Semiconductor Conference - CAS 2021, 8 October 2021 – prezentare orală (online).

3. R. Balint, Gh. Tomoaia, D. Oltean-Dan, A. Mocanu, M. Tomoaia-Cotisel, "Nanomaterials with enhanced biological function for bone regeneration", Conferinţa Ştiinţifică de Primăvară a AOSR, 2021, Bucureşti, 10-11 iunie 2021, Volum de rezumate, pag. 66, online, prezentare orală.

4. R. Balint, Gh. Tomoaia, S. Riga, A. Mocanu, M. Tomoaia-Cotisel, "Scafolduri din compozite biomimetice cu hidroxiapatită multisubstituită şi colagen pentru aplicaţii biomedicale", Conferinţa Ştiinţifică Naţională de Toamnă – Tradiţii şi progrese în ştiinţa românească, AOSR, 2021, Bucureşti, 18-20 Noiembrie, 2021, Secţiunea ştiinţe biologice, Volum de rezumate, pag. 24, online, prezentare orală.

5. A. Avram, A. Mocanu, Gh. Tomoaia, S. Riga, M. Tomoaia-Cotisel, "Efectul condiţiilor de sinteză asupra bioactivităţii nanoparticulelor de Mg2SiO4", Conferinţa Ştiinţifică Naţională de Toamnă – Tradiţii şi progrese în ştiinţa românească, AOSR, 2021, Bucureşti, 18-20 Noiembrie, 2021, Secţiunea ştiinţe biologice, Volum de rezumate, pag. 24-25, online, prezentare orală.

6. G.A. Paltinean, S. Riga, Gh. Tomoaia, A. Mocanu, M. Tomoaia-Cotisel, "Compuşi bioactivi din plante utilizaţi ca agenţi terapeutici în aplicaţii biomedicale", Conferinţa Ştiinţifică Naţională de Toamnă – Tradiţii şi progrese în ştiinţa românească, AOSR, 2021, Bucureşti, 18-20 Noiembrie, 2021, Secţiunea ştiinţe biologice, Volum de rezumate, pag. 26-27, online, prezentare orală.

7. R. Balint, A. Mocanu, M. Tomoaia-Cotisel, "Preparation and Characterization of Nanohydroxyapatites Doped with Various Biological Active Compounds with Biomedical Applications", Conferinţa Ştiinţifică Naţională de Toamnă, AOSR, 2021, NanoBio Mat 2021, - Applications of Chemistry in Nanosciences and Biomaterials Engineering, 25-27 November, 2021, Bucharest, online, prezentare orală.




·   Phase 3 Dissemination:

Research original articles (ISI/BDI)

1. C. G. Floare, M. Bogdan, M. Tomoaia-Cotişel, A. Mocanu, “1H NMR spectroscopic characterization of inclusion complex of desferrioxamine B chelator and cyclodextrin”, Journal of Molecular Structure, 1248, 131477, (2022). https://doi.org/10.1016/j.molstruc.2021.131477

2. A. Avram, S. Rapuntean, M. Gorea, Gh. Tomoaia, A. Mocanu, O. Horovitz, Gh. Rapuntean, M. Tomoaia-Cotisel,”In vitro antibacterial effect of forsterite nanopowder: synthesis and characterization”, Environmental Science and Pollution Research, (8 June 2022). https://doi.org/10.1007/s11356-022-21280-0.

3. L. Z. Rácz, Cs.-P. Rácz, O. Horovitz, Gh. Tomoaia, A. Mocanu, I. Kacso, M. Sárközi, M. Dan, S. Porav, G. Borodi, M. Tomoaia-Cotisel, “Complexation of Curcumin using Whey Proteins to Enhance Aqueous Solubility, Stability and Antioxidant Property”, Studia Ubb Chemia, 67 (3) 75-99, 2022.

4. L. Z. Rácz, G.-A. Paltinean, I. Petean, Gh. Tomoaia, L. C. Pop, G. Arghir, E. Levei, A. Mocanu, Cs.-P. Rácz, M. Tomoaia-Cotisel, “Curcumin and Whey Protein Binding and Structural Characteristics of their Complex Evidenced by Atomic Force Microscopy”, Studia Ubb Chemia, 67 (3), 61-74, 2022.

5. D. Gonciar, T. Mocan, L. Agoston-Coldea, “Nanoparticles Targeting the Molecular Pathways of Heart Remodeling and Regeneration”, Pharmaceutics, 14, 711, 2022.

6. R. Balint, G. A. Paltinean, D. Florea, Gh. Tomoaia, A. Mocanu, M. Tomoaia-Cotisel, “Biomimetic and Antibacterial Composite for Orthopedic Implants”, Academy of Romanian Scientists, Annals Series of Biological Sciences, 11(1), 120-145, (2022). 

7. L. Z. Rácz, Cs. P. Rácz, L. C. Pop, Gh. Tomoaia, A. Mocanu, I. Barbu, M. Sárközi, I. Roman, A. Avram, M. Tomoaia-Cotisel, V.-A. Toma, „Strategies for improving bioavailability, bioactivity, and physical-chemical behavior of the curcumin”, Molecules, Special Issue Thermodynamics, Structure and Intermolecular Interactions in Solutions, 2022, 27 (20), 6854. https://doi.org/10.3390/molecules27206854

8. G. A. Paltinean, Gh. Tomoaia, S. Riga, A. Mocanu, M. Tomoaia-Cotisel, “Silymarin based complexes – a mini review”, Academy of Romanian Scientists, Annals Series of Biological Sciences, 11(1), 146-166, (2022).

9. A. Avram, A. Mocanu, Gh. Tomoaia, M. Tomoaia-Cotisel, “Review on the Biocompatibility and Bioactivity of Forsterite: In Vitro and in Vivo studies”, Academy of Romanian Scientists, Annals Series of Biological Sciences, 11(1), 167-190, (2022).

 

Communications at conferences

1. A. Avram, A. Mocanu, Gh. Tomoaia, T. Mocan, M. Tomoaia-Cotisel, ENG: “Hydroxyapatite as a carrier for an efficient delivery of D3 and K2 vitamins”, Conferinţa Ştiinţifică Naţională de Primăvară „Era digitală – Provocări şi Oportunităţi pentru Societatea Contemporană”, AOSR 2022 , 6-7 May, Bucharest, Sectiunea biologie, Volum de rezumate, pag.101-102 (2022), on-line, oral presentation.

2. A. Avram, A. Mocanu, O. Horovitz, Gh. Tomoaia, S. Riga, M. Tomoaia- Cotisel, “Nanocomposites based on hydroxyapatite and vitamins”, Virtual International Scientific Conference on “Applications of Chemistry in Nanosciences and Biomaterials Engineering” NanoBioMat 2022, 22-24 June, Bucharest, on-line, oral presentation on Session III: Biomaterials for Tissue Engineering and Regeneration.

3. G.A. Paltinean, Gh. Tomoaia, S. Riga, A. Mocanu, M. Tomoaia-Cotisel, “Silymarin Based Complexes”, Conferinţa Ştiinţifică Naţională de Primăvară „Era digitală – Provocări şi Oportunităţi pentru Societatea Contemporană”, AOSR 2022, 6-7 May, Bucharest, Sectiunea biologie, Volum de rezumate, pag.102 (2022), on-line, oral presentation.

4. A. Avram, A. Mocanu, Gh. Tomoaia, S. Riga, M. Tomoaia-Cotisel, “Composites for bone regeneration. Nanotechnological applications in biomedicine”, Conferinţa Ştiinţifică Naţională de Primăvară „Era digitală – Provocări şi Oportunităţi pentru Societatea Contemporană”, AOSR 2022, 6-7 May, Bucharest, Sectiunea de medicina, Volum de rezumate, pag.121-122 (2022), on-line, oral presentation.


Patent proposal

M.Tomoaia-Cotisel, A. Mocanu, Gh. Tomoaia, O. Horovitz, A. Pop, A. Avram, O. Cadar, T.Mocan, C. Roman, A. Becze, “Nanocomposites based on hydroxyapatite and vitamins. Obtaining process”, Cerere de brevet CBI a nr. A/00370 OSIM, Bucuresti, 30.06.2022.