Web of knowledge for

NANOSILVA

Contract number 83/2017

National Authority: UEFISCDI

UNIVERSITATEA BABES BOLYAI

FACULTATEA DE CHIMIE SI INGINERIE CHIMICA

 

Innovative composites with antimicrobial properties comprising ceramic nanoparticles and silver nanoparticles, functionalized with biomolecules, embedded into polymer matrix

 

 

 

 

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OBJECTIVES

EXPECTED RESULTS

OBTAINED RESULTS

DISSEMINATION

 

 

 

 

 

 

·   Phase 1 Dissemination:

• Research original articles (ISI)

1) O. Cadar, R. Balint, Gh. Tomoaia, D. Florea, I. Petean, A. Mocanu, O. Horovitz,

and M. Tomoaia-Cotisel,
Behavior of multi-substituted hydroxyapatites in water and simulated body fluid,
Studia UBB Chemia, 62, 4, Tom II, 269-281, 2017.

 

2) O. Cadar, P. T. Frangopol, G. Tomoaia, D. Oltean, G. A. Paltinean, A. Mocanu, O. Horovitz,

and M. Tomoaia-Cotisel ,
Silicon release from hydroxyapatites in water and simulated body fluid,
Studia UBB Chemia, 62, 4, Tom I, 67-80, 2017.

 

3) A. Avram, T. Frentiu, O. Horovitz, A. Mocanu, F. Goga, and M. Tomoaia-Cotisel,
Hydroxyapatite for Removal of Heavy Metals From Wastewater,
Studia UBB Chemia, 62, 4, Tom I, 93 – 104, 2017.

 

4) E. Forizs, F. Goga, A. Avram, A. Mocanu, I. Petean, O. Horovitz, and M. Tomoaia-Cotisel

Thermal Analysis of Pure and Multisubstituted Hydroxyapatite Pastes,
Studia UBB Chemia, 62, 4, Tom I, 173 - 180, 2017.


• Communications at conferences and workshops/seminars

1) M. Tomoaia-Cotisel and A. Mocanu,
Frontier research in advanced nanostructured hydroxyapatites,
Keynote Speech and invited session chair, 2017 International Conference on Materials Sciences

and Nanomaterials (ICMSN 2017), Barcelona, Spain, 14-16 July, 2017.

2) M. Tomoaia-Cotisel,
Multifunctional ceramics for antimicrobials delivery,
COST Action MP1301, New Generation Biomimetic and Customized Implants for Bone

Engineering. Vienna, Austria, 28 -29 August, 2017.

 

3) M. Tomoaia-Cotisel,

Turning antimicrobial discoveries into health applications,

Scientific Conference Session of Academy of Romanian Scientists, Timisoara, Romania,

11 October, 2017.

 

Seminars/Workshops

 

4) A. Mocanu, M. Tomoaia-Cotisel and G. A. Paltinean,

Sintering of hydroxyapatite powder loaded with antimicrobials,

Seminar, University of Bordeaux, "High pressure, Sintering and Thin films lab",

Bordeaux, France, 8 November, 2017.

 

5) M. Tomoaia-Cotisel, A. Mocanu, O. Horovitz, G.A. Paltinean, G. Demazeau,

A. Largeteau and A. Plumecocq,

Sterilization of hydroxyapatite pastes loaded with silver nanoparticles under high hydrostatic pressure,

Seminar, University of Bordeaux, "High pressure lab", Bordeaux, France, 13 November, 2017.

 

·   Phase 2 Dissemination:

• Research original articles (ISI)

1) S. Rapuntean, R.Balint, G.A. Paltinean,G. Tomoaia, A. Mocanu, Cs.-P. Racz, O. Horovitz,

and M. Tomoaia-Cotisel,
Antibacterial activity of silver nanoparticles obtained by co-reduction with sodium citrate and tannic acid,
Studia UBB Chemia, 63, 3, 73-85, 2018.

2) S. Rapuntean, P.T. Frangopol, I. Hodisan, G. Tomoaia, D. Oltean-Dan, A. Mocanu, C. Prejmerean,

O. Soritau, L.Zs. Racz, and M. Tomoaia-Cotisel,
In vitro response of human osteoblasts cultured on strontium substituted hydroxyapatites,
Revista de Chimie, 69 (12), 3537-3544, 2018.


• Communications at conferences and workshops/seminars

1) M. Tomoaia-Cotisel,
“Innovative strategies for the development of advanced multi-functional nanomaterials and biomedical applications”,
Keynote Speech, ICSEM 2018, International Conference on Smart Engineering Materials 7-9 March, 2018, Bucharest, Romania, Keynote Speaker Certificate; Conference Chair Certification.

2) M. Tomoaia-Cotisel,
”Development of functional nanomaterials: from multi-functional bio-interfaces to biomaterials and tissue engineering”,
Keynote Speech, ICMSN 2018, The second International Conference on Materials Sciences and Nanomaterials, Liverpool, U.K., July 11-13, 2018; Keynote Speaker Certificate; Certificate for Conference Chair .

3) M.Tomoaia-Cotisel,
”Advanced nanostructured materials: Turning scientific discoveries into health”,
Keynote Speech on Aug. 20, 2018, ICMSMC 2018, International Conference on Materials Science and Materials Chemistry, August 20-22, 2018, Paris, France; Certificate of Recognition for Keynote Presentation.

4) M. Tomoaia-Cotisel,
”Drug Delivery Systems”,
Keynote Speech at Workshop on “Antibacterial activity of nanostructured biomaterials”, on Aug 21, 2018, ICMSMC 2018 – International Conference on Materials Science and Materials Chemistry, August 20-22, 2018, in Paris, France; Certificate of Recognition for Keynote Presentation; Certificate of Recognition for chairing the sessions on Materials Chemistry Research/ Nanomaterials / Biomaterials/ Energy Materials/ Liquid Crystals.

5) G. A. Paltinean, A. Mocanu, G. Tomoaia, S. Rapuntean, I. Petean, O. Horovitz, and M. Tomoaia, Cotisel,
“Antimicrobial activity of vancomycin loaded in biomimetic hydroxyapatite and poly (lactic acid) microcapsules”,

oral presentation on August 20, 2018. Poster presentation: Workshop about “Antibacterial activity of nanostructured biomaterials”, on August 21, 2018, ICMSMC 2018, August 20-21, Paris, France.

6) R. Balint, G. Tomoaia, S. Rapuntean, A. Mocanu, O. Horovitz, and M. Tomoaia-Cotisel,

“Novel composites based on nanoceramics and silver nanoparticles with antimicrobial activity

for biomedical applications”,

oral presentation on August 20, 2018.  Poster presentation: Workshop about “Antibacterial activity of

nanostructured biomaterials”, on August 21, 2018, ICMSMC 2018, August 20-21, Paris, France.

7) Al. Avram, A.M. Naghiu, M. Gorea, and M. Tomoaia-Cotisel,
“Forsterite porous nanoceramics as a novelty in medical applications”

oral presentation on August 20, 2018. Poster presentation: Workshop on “Antibacterial activity of

nanostructured biomaterials”, on August 21, 2018, ICMSMC 2018, August 20-21, Paris, France.

Poster presentation.

8) Gh. Tomoaia and M. Tomoaia-Cotisel,
”Bioactive coatings made of collagen and hydroxyapatite composites for innovative orthopedic implants”,
Keynote Speech, ARA Congress 2018: American Romanian Academy of Arts and Sciences

(ARA: Academy Headquarters: University of California, Davis, One Shields Avenue, Davis,

CA 95616), May 23-26, 2018, Cluj-Napoca, Romania.

9) M. Tomoaia-Cotisel, A. Mocanu, and Gh. Tomoaia,
”In vitro response of human osteoblasts to biomimetic hydroxyapatite ceramics”,

Plenary Conference, ARA Congress 2018, May 23-26, 2018, Cluj-Napoca, Romania.

10) Gh.Tomoaia and M. Tomoaia-Cotisel,
“Orthopedic coatings made of bioceramics and silver nanoparticles for antimicrobial therapy”,
Plenary Conference, AOSR 2018 – Conferinta Nationala de Primavara a Academiei Oamenilor de

Stiinta din Romania, AOSR, 30 Martie 2018, Bucuresti,, Romania, cu participare internationala.


11) Gh. Tomoaia and M. Tomoaia-Cotisel,
“Translating gold nanoparticles and their complexes with biomolecules to therapeutics”,

Plenary Conference, AOSR 2018 – Conferinta Nationala de Primavara a Academiei Oamenilor de

Stiinta din Romania, AOSR, 30 Martie 2018, Bucuresti,, Romania, cu participare internationala.

 

Seminars/Workshops

 

Comunicarile stiintifice [4-7] au avut loc si la Workshopul, cu participare internationala organizat de echipa de cercetare NanoSilva la ICMSMC 2018 – International Conference on Materials Science and Materials Chemistry, August 21, 2018, in Paris, France. Workshop on “Antibacterial activity of nanostructured biomaterials”, on August 21, 2018, ICMSMC 2018.

 

·   Phase 3 Dissemination:

• Research original articles (ISI)

1) R. Balint, G. A. Paltinean, A.Mocanu, O. Horovitz, M.Tomoaia-Cotisel,
“Interaction of silver nanoparticles with vancomycin: an Uv-vis study”,
Studia UBB Chemia, 64, (2), Tom II, 335-343, 2019.

 

2) C. Garbo, J. Locs, M. D’Este, G. Demazeau, A. Mocanu, C. Roman,

O. Horovitz, M. Tomoaia-Cotisel,

“Advanced Mg, Zn, Sr, Si multi-substituted hydroxyapatites for bone regeneration:

Synthesis and physico-chemical characterisation”,

Int. J. Nanomed., 2019 in press.


3) A. Avram, M. Gorea, S. Rapuntean, A. Mocanu, G. A. Paltinean, Cs. Varhelyi Jr.,

I. Petean, O. Horovitz, M. Tomoaia-Cotisel,

“The in-vitro antibacterial activity of novel nanostructured composites based on forsterite and silver nanoparticles”,

Rev. Chim., (Bucharest), 2019, in press.


4) M.Gorea, M-A Naghiu, A.Avram, I.Petean, M. Tomoaia-Cotisel,
“Sintering and characterization of new forsterite ceramics”,
Studia UBB Chemia, 64 (2), Tom II, 383-392, 2019.
 

5) M. Gorea, M.-A. Naghiu, A. Avram, I. Petean, A. Mocanu, M. Tomoaia-Cotisel,

“Novel porous forsterite ceramics. Biocompatibility and bioactivity evaluation”,

Rev. Chim., (Bucharest), 2019, in press.
 

• Communications at conferences and workshops/seminars

1) M.Tomoaia-Cotisel,

“Advanced engineering materials for bone regeneration”,

The 4th International Conference on Smart Engineering Materials (ICSEM 2019),

March 9-11, 2019, Auckland, New Zealand.


2) M.Tomoaia-Cotisel,

“Advanced Nanomaterials for Enhanced Bone Consolidation and Fracture Healing”,

3rd International Conference on Materials Sciences and Nanomaterials (ICMSN 2019),

July 22-24, 2019 University of Oxford, the United Kingdom.


3) G. A. Paltinean, R. Balint, A. Mocanu, Gh. Rapuntean, I. Petean, O. Horovitz and M. Tomoaia-Cotisel,

“Antimicrobial activity of poly lactic acid microspheres loaded with vancomicin”,

12th International Conference "Processes in Isotopes and Molecules” (PIM),

25-27 September, 2019, Cluj-Napoca, Romania.


4) A. Avram, M Gorea, A Mocanu and M Tomoaia-Cotisel,

“The influence of synthesis methods on the characteristics of porous forsterite ceramics”,

12th International Conference "Processes in Isotopes and Molecules” (PIM),

25-27 September, 2019, Cluj-Napoca, Romania.


5) M. A. Ujica, A. Mocanu, D.A. Chira and M. Tomoaia-Cotisel,
“Challenges in metallic nanoparticles synthesis and prospective applications”
12th International Conference "Processes in Isotopes and Molecules” (PIM),

25-27 September, 2019, Cluj-Napoca, Romania.

6) R Balint, S Rapuntean, A Mocanu, O Horovitz and M Tomoaia-Cotisel,
“New antibacterial systems for biomedical applications”,
12th International Conference "Processes in Isotopes and Molecules” (PIM),

25-27 September, 2019, Cluj-Napoca, Romania.

 

7) A. Avram, M Gorea, A Mocanu and M Tomoaia-Cotisel,
“Cercetarea si dezvoltarea unor compozite formate din forsterit, colagen si PLA depuse pe implanturi metalice”,
Conferinta Nationala Stiintifica Academia Oamenilor de Stiinta din Romania,

20-21 Septembrie, 2019, Brasov, Romania

8) M. A. Ujica, M. Tomoaia-Cotisel, A. Mocanu and O.Horovitz,
“Nanoparticule de aur si argint: de la sinteza la aplicatii”,
Conferinta Nationala Stiintifica Academia Oamenilor de Stiinta din Romania,

20-21 Septembrie, 2019, Brasov, Romania
 

• Patents

1) A. Mocanu, O. Horovitz, S. Rapuntean, A. Pop, G - A Paltinean, M Tomoaia – Cotisel,

“ Sisteme antimicrobiene care contin nanoparticule de argint si antibiotic pentru aplicatii

biomedicale: preparare si caracterizare”,

cerere brevet nr. a 2019 00279 din 13.05.2019.

 

• Seminars/Workshops

 

Workshop NanoSilva, la Conferinta Nationala Stiintifica a Academiei Oamenilor de Stiinta din Romania (AOSR), Sesiunea de toamna a AOSR, Brasov,19-21 Septembrie 2019. Au fost prezentate 5 lucrari stiintifice de membrii echipei de cercetare NanoSilva pe data de 21 Septembrie la Worshopul NanoSilva 2019 organizat in cadrul sesiunii de Comunicari Stiintifice la sectiunea de Stiintele Medicale.


1) G.A. Paltinean, A. Mocanu, M. Tomoaia-Cotisel, Gh. Tomoaia,

“Materiale inovatoare pentru ingineria tisulara a oaselor osteoporotice”,

Conferinta nationala stiintifica, « Convergenta reala Romania-Uniunea Europeana, CRUE », Academia Oamenilor de Stiinta din Romania, 13(2), 2019, 20-21 Septembrie, Brasov; ISSN 2601-5102; Abstract, pages 81-82; Prezentare Orala; Workshop NanoSilva in cadrul sesiunii de comunicari la Stiinte Medicale.


2) M.-A. Ujica, M. Tomoaia-Cotisel, A. Mocanu, O. Horovitz,

“Nanoparticule de aur si argint: de la sinteza la aplicatii”,

Conferinta nationala stiintifica, « Convergenta reala Romania-Uniunea Europeana, CRUE », Academia Oamenilor de Stiinta din Romania, 13(2), 2019, 20-21 Septembrie, Brasov; ISSN 2601-5102; Abstract, page 80; Prezentare Orala; Workshop NanoSilva in cadrul sesiunii de comunicari la Stiinte Medicale.


3) A. Avram, M. Gorea, A. Mocanu, M. Tomoaia-Cotisel,

“Cercetarea si dezvoltarea unor compozite formate din forsterit, colagen si PLA depuse pe implanturi metalice”,

Conferinta nationala stiintifica, « Convergenta reala Romania-Uniunea Europeana, CRUE », Academia Oamenilor de Stiinta din Romania, 13(2), 2019, 20-21 Septembrie, Brasov; ISSN 2601-5102; Abstract, page 79; Prezentare Orala ; Workshop NanoSilva in cadrul sesiunii de comunicari la Stiinte Medicale.


4) R. Balint, M. Tomoaia-Cotisel, G. Tomoaia,

“Compozite biomimetice avansate utilizate în captusirea implantelor metalice pentru vindecarea fracturilor osoase”,

Conferinta nationala stiintifica, « Convergenta reala Romania-Uniunea Europeana, CRUE », Academia Oamenilor de Stiinta din Romania, 13(2), 2019, 20-21 Septembrie, Brasov; ISSN 2601-5102; Abstract, pages 80-81; Prezentare Orala; Workshop NanoSilva


5) D. Oltean-Dan, G. Tomoaia, M. Tomoaia-Cotisel,

“Optiuni terapeutice moderne în tratamentul osteoporozei si al fracturilor asociate”,

Conferinta nationala stiintifica, « Convergenta reala Romania-Uniunea Europeana, CRUE », Academia Oamenilor de Stiinta din Romania, 13(2), 2019, 20-21 Septembrie, Brasov; ISSN 2601-5102; Abstract, page 82; Prezentare Orala; Workshop NanoSilva in cadrul sesiunii de comunicari la Stiinte Medicale.